Unrealistic optimism is a bias that leads people to believe, with respect to a specific event or hazard, that they are more likely to experience positive outcomes and/or less likely to experience negative outcomes than similar others. The phenomenon has been seen in a range of health-related contexts—including when prospective participants are presented with the risks and benefits of participating in a clinical trial. In order to test for the prevalence of unrealistic optimism among participants of early-phase oncology trials, we (...) conducted a survey with patients over 18 years of age who were enrolled in a phase I, phase I/II, or phase II clinical cancer trial in the New York City area between August 2008 and October 2009. Participants in our study were asked to compare their own chances of experiencing a range of risks and benefits related to the trial they were enrolled in with the chances of the other trial participants. We found a significant optimistic bias in their responses. Respondents tended to overestimate the benefits of the trial they were enrolled in and underestimate its risks. In addition, we found no significant relationship between respondents’ understanding of the trial’s purpose and how susceptible they were to unrealistic optimism. Our findings suggest that improving the consent process for oncology studies requires more than addressing deficits in understanding. (shrink)

1 Evidence-based policy requires researchers to provide the answers to ecological questions that are of interest to policy makers. To find out what those questions are in the UK, representatives from 28 organizations involved in policy, together with scientists from 10 academic institutions, were asked to generate a list of questions from their organizations. 2 During a 2-day workshop the initial list of 1003 questions generated from consulting at least 654 policy makers and academics was used as a basis for (...) generating a short list of 100 questions of significant policy relevance. Short-listing was decided on the basis of the preferences of the representatives from the policy-led organizations. 3 The areas covered included most major issues of environmental concern in the UK, including agriculture, marine fisheries, climate change, ecosystem function and land management. 4 The most striking outcome was the preference for general questions rather than narrow ones. The reason is that policy is driven by broad issues rather than specific ones. In contrast, scientists are frequently best equipped to answer specific questions. This means that it may be necessary to extract the underpinning specific question before researchers can proceed. 5 Synthesis and applications. Greater communication between policy makers and scientists is required in order to ensure that applied ecologists are dealing with issues in a way that can feed into policy. It is particularly important that applied ecologists emphasize the generic value of their work wherever possible. (shrink)

RÉSUMÉ : Dans son récent recueil d’articles Language, Truth and History, Donald Davidson semble pencher en faveur d’une philosophie du langage mettant l’accent sur la notion de l’intention communicative du sujet parlant; en quoi il se rapproche du point de vue de Paul Grice. Si cela est juste, la pensée de Davidson se serait dégagée de l’approche sémantique formelle qu’il soutenait dans ses Inquiries into Truth and Interpretation. Dans cet article, je soutiens que, bien qu’il y ait beaucoup de (...) similitudes entre ces deux penseurs, Davidson n’a pas abandonné ses précédentes vues sur le langage. (shrink)

Essays on Philosophy and Economic Methodology By Daniel M. Hausman Cambridge University Press, 1992. Pp. 259. ISBN 0?521?41740?6. £35.00. Le Fondement de la morale: Essai d'éthiquephilosophique By André Léonard Cerf, 1991. Pp. 381. ISBN not available. FF240. The Philosophy of Time Edited By Robin Le Poidevin and Murray MacBeath Oxford University Press, 1993. Pp. 230. ISBN 0?19?823998?X. £27.50. The Ethics and Politics of Human Experimentation By Paul M. McNeill Cambridge University Press, 1993. Pp. 315. ISBN 0?521?41627?2. £35.00. Modern Conditions, (...) Postmodern Controversies By Barry Smart Routledge, 1991. Pp. 241. ISBN 0?415?06952. £10.99. Religion in Relation. Method, Application and Moral Location By Ivan Strenski Macmillan, 1993. Pp. ix + 257. ISBN 0?333?53469?7. £45.00. Robert Nozick: Property, Justice and the Minimal State By Jonathan Wolff Polity Press, 1991. Pp. ix + 168. ISBN 0?7456?0603?2. £8.95 pbk. (shrink)

Huw Price’s subject naturalism has emerged as a leading pragmatist position within recent debates surrounding philosophical naturalism. Unlike orthodox views which tend to be guided by metaphysical questions about the “place” of, for instance, the mind, meaning, and morality within the natural world, subject naturalism focuses philosophical attention on language-users and the functions that certain concepts play within discursive practices. This paper considers two objections to subject naturalism and argues that they can be overcome by looking to the methodological insights (...) of philosophical genealogy. Although Price occasionally characterizes his project as a kind of genealogy, he offers little explanation of what such a methodological orientation is supposed to involve. I suggest that subject naturalists ought to remedy this theoretical lacuna by looking to the work of Bernard Williams. On the one hand, doing so can serve a diagnostic function: Williams’ conception of genealogy affords a perspective from which subject naturalism’s explanatory inadequacies are more clearly understood. On the other hand, Williams’ elaborated conception of genealogy represents a path by which the subject naturalist can overcome the shortcomings discussed in this paper. (shrink)

Of the six basic categories which a normative ethical theory may recognize and exemplify, The first five are fairly clearly employed by kant in the "tugendlehre", But the sixth is not given adequate recognition by him. In order to establish those conclusions, One has to investigate the leading notion of the "tugendlehre", That of obligatory ends. Closely connected with that notion is kant's division of duties into perfect and imperfect ones. Consideration of a number of ways of elucidating that division (...) leads one to conclude that it is not really so sharp as kant suggests. The sphere of duty comprises a continuum of duties of wider and of narrower obligation; beyond that sphere belong many things which one morally "ought" to prize and to pursue, But which do not constitute obligatory ends for men. (shrink)

We propose that synesthetic cross‐activation between the primary auditory cortex and the anatomically adjacent insula may help explain two puzzling conditions—autonomous sensory meridian response (ASMR) and misophonia—in which quotidian sounds involuntarily trigger strong emotional responses. In ASMR the sounds engender relaxation, while in misophonia they trigger an aversive response. The insula both plays an important role in autonomic nervous system control and integrates multiple interoceptive maps representing the physiological state of the body to substantiate a dynamic representation of emotional wellbeing. (...) We propose that in ASMR cross‐activation of the map for affective (sensual) touch leads to an increase in subjective wellbeing and parasympathetic activity. Conversely, in misophonia the effect of the cross‐activation is to decrease emotional wellbeing and increase sympathetic activity. Our hypothesis also illuminates the connection between hearing and wellbeing more broadly and helps explain why so many people experience decreased wellbeing from modern urban soundscapes. (shrink)

This commentary critically examines two facets of Tracy Llanera's recent book Richard Rorty: Outgrowing Modern Nihilism. First, it considers her interpretation of Richard Rorty's redemptive project. It argues that, while Llanera succeeds in resolving tensions in Rorty's public‐private distinction, her account downplays the role of abnormal discourse within projects of self‐creation. Second, it raises several questions about Llanera's strategy for situating this redemptive project within debates concerning existential nihilism. On her view, one ought to follow Rorty in addressing the problem (...) of egotism instead of the problem of nihilism, since the former is prior to the latter. But it is not clear who counts as an egotist, or why egotists are especially prone to becoming nihilists. Moreover, there are reasons to think that egotism and nihilism are fundamentally different kinds of problems. (shrink)

The present article illustrates a conflict between the claim that rational belief sets are closed under deductive consequences, and a very inclusive claim about the factors that are sufficient to determine whether it is rational to believe respective propositions. Inasmuch as it is implausible to hold that the factors listed here are insufficient to determine whether it is rational to believe respective propositions, we have good reason to deny that rational belief sets are closed under deductive consequences.

The present paper introduces a simple framework for modeling the relationship between environmental states, perceptual states, and action. The framework represents situations where an agent’s perceptual state forms the basis for choosing an action, and what action the agent performs determines the agent’s payoff, as a function of the environmental conditions in which the action is performed. The framework is used as the basis for a simulation study of the sorts of correspondence between perceptual and environmental states that are important (...) for successful navigation of the world. Some of the results are surprising and conflict with long held views about the kind of perception-to-environment correspondence that is important for knowledge of the world. The results also raise doubts concerning the view that our perceptual states provide a basis for knowledge of the real structure of the external world. (shrink)

This article presents results from a simulation‐based study of inheritance inference, that is, inference from the typicality of a property among a “base” class to its typicality among a subclass of the class. The study aims to ascertain which kinds of inheritance inferences are reliable, with attention to the dependence of their reliability upon the type of environment in which inferences are made. For example, the study addresses whether inheritance inference is reliable in the case of “exceptional subclasses” (i.e., subclasses (...) that are known to be atypical in some respect) and attends to variations in reliability that result from variations in the entropy level of the environment. A further goal of the study is to show that the reliability of inheritance inference depends crucially on which sorts of base classes are used in making inferences. One approach to inheritance inference treats the extension of any atomic predicate as a suitable base class. A second approach identifies suitable base classes with the cells of a partition (of a preselected size k) of the domain of objects that satisfies the condition of maximizing the similarity of objects that are assigned to the same class. In addition to permitting more inferences, our study shows that the second approach results in inheritance inferences that are far more reliable, particularly in the case of exceptional subclasses. (shrink)

In Situations and Individuals, Paul Elbourne argues that the natural language expressions that have been taken to refer to individuals — pronouns, proper names, and definite descriptions — have a common syntax and semantics, roughly that of definite descriptions as construed in the tradition of Frege. In the course of his argument, Elbourne shows that proper names have previously undetected donkey anaphoric readings.This is contrary to previous theorizing and, if true, would undermine what philosophers call the direct reference theory (...) (which holds that the sole contribution of a proper name to the truth conditions of a sentence is an individual) as well as the related doctrine that proper names are rigid designators. Elbourne begins by addressing donkey anaphora, relating other concerns about pronouns to the solution of this notorious problem. His subsequent argumentation provides a unified semantics for the donkey anaphoric and bound and referential uses of pronouns and discusses the prospect of unifying the syntax and semantics of pronouns with the syntax and semantics of normal definite descriptions. Elbourne's aim is not only to advance his proposal of a unified syntax and semantics but also to urge linguists and philosophers dealing with pronoun interpretation to consider a wider range of theories than they do at present, and to test the competing claims of description-based theories and dynamic semantics against the data. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:From Epistemology to EthicsPaul D. NumrichThe evolution of the essays gathered here began as I pondered a popular article about contemporary science-religion dialogue some years ago. I was reminded that Christian notions provide the motivation, presuppositions, and conclusions for much of this dialogue and wondered, "How might things differ if Buddhism joined the conversation?" I later learned that others wondered likewise and that the John Templeton Foundation was willing (...) to fund a project to explore the contours of a Buddhism-Christianity-science dialogue.As important as all this was, the project took an early epistemological turn, to borrow a phrase from Mark T. Unno's chapter in the eventual edited volume, The Boundaries of Knowledge in Buddhism, Christianity, and Science.1 The project's advisors recommended that we not devolve into simplistic litanies of how the latest scientific theories confirm ancient religious wisdom or how religions might accommodate the latest scientific discoveries. They also counseled that we should avoid narrowly construed theoretical or doctrinal discussions. Instead, we should focus on "knowability" in science and religion. And we should challenge the hubris that claims to know everything—or everything that really matters—whether that hubris presumes to speak for science or for religion.The Boundaries of Knowledge in Buddhism, Christianity, and Science addresses the really big philosophical question "What can we know about reality?" and inquires into profound epistemological issues that cut across the worldviews of Buddhism, Christianity, and science: How do they explore the boundaries between the known and the unknown? What do they define as unknowable? How do they participate in the human quest for knowledge about reality? The volume goes beyond the usual fare in contemporary science-religion dialogue to explore how science and religion engage each other's attempts to understand reality.In the opening chapter, I ruminate on human knowledge generally. The other chapters move largely from Buddhism to Christianity to science, although several incorporate insights from more than one of these worldviews. Project advisor Roger Blomquist of Argonne National Laboratory suggested the important distinction between a boundary (which is movable) and a limit (which is fixed, i.e., the ultimate boundary). The frontiers of knowledge are often pushed back in both science and religion, yet these shifting boundaries exist within a larger fixed limit of human knowability. What Buddhists, Christians, and scientists do in the face of moveable boundaries within a fixed limit of knowability provides the intrigue of the volume. The contributors were not required to honor the distinction between moveable boundaries and a fixed limit. At times these terms are used interchangeably, at other times the distinction is implicitly called into question, thus adding to the volume's intrigue.The physicist-philosopher Niels Bohr (1885-1962) pondered the inherent inadequacy of conceptualization and language in apprehending and explaining reality. His assistant relates a discussion between Bohr and unnamed others: "He [Bohr] was forcefully stressing the primacy of language: 'Ultimately, we human beings depend on our words. We are hanging in language.' When it was objected that reality is more fundamental than language and lies beneath language, Bohr answered: 'We are suspended in language in such a way that we cannot say what is up and what is down.'"2Religions understand the human condition of being suspended in languages that cannot contain perceived realities. Hence their frequent use of metaphor, symbolism, via negativa statements, and the notion of "mystery." Here is a fruitful opening for dialogue between science and religion, offering an opportunity for mutual pondering of the limit of pondering. The volume presents Buddhism, Christianity, and science as case studies in the human endeavor to understand a reality tantalizingly beyond our ability to understand fully. It examines the epistemological conundrums at the boundaries and limit of human [End Page 161] knowledge, where at some point both conceptualization and language inevitably fail us.The essays gathered here were given in early versions at the 2009 annual meeting of the Society for Buddhist-Christian Studies. Paul O. Ingram and Dennis Hirota gave presentations based on their chapters in The Boundaries of Knowledge in Buddhism, Christianity, and Science, to which Sandra Costen Kunz and Amos Yong, respectively, gave responses. These four presentations... (shrink)

Despite widespread interest in the topic of moral repair in the business ethics literature and in the workplace, little is currently known about moral repair with regard to the self—i.e., how and why individuals repair themselves in the aftermath of harming others within workplace contexts and what factors may influence the success of self-repair. We conducted a qualitative study in the context of health care organizations to develop an inductive model of self-repair in the workplace. Our findings reveal a set (...) of factors, including reactions to the harm incident, motivating factors, and methods of self-repair that involve intrapersonal (e.g., self-compassion) and interpersonal (e.g., seeking feedback and support from co-workers and managers) actions. We discovered that self-repair, or what we characterize as “moral self-repair” is a complex process characterized by important ethical, emotional, and social dimensions and that the effectiveness of self-repair actions is moderated by the actions of those within the organization (e.g., co-workers, managers) and outside the organization (e.g., families, friends, counselors). These social actors can promote self-repair by offering encouragement and support, or undermine self-repair by communicating a lack of trust and respect that reinforces self-blame. This model of self-repair is intended to guide future ethics research on the topic of moral self-repair and offers insight to practicing managers. (shrink)

The thesis of this paper is that the Tractatus and the Investigations can be related as follows. Wittgenstein attempted in the Tractatus to avoid the conceptual realism of Frege and Russell with respect to propositions. He solved his problem by developing the picture-theory of language. This solution assumed that the units of language are words which arc names of simple objects. Because of this assumption the solution has the undesirable consequence that examples oi genuine names, atomic facts and atomic propositions (...) cannot be given although their existence is logically required by the solution. Wittgenstein had, therefore, eventually to examine the idea of a name. Thus the Philosophical Investigations in which this examination is conducted. (shrink)

As in previous stochastic interpretations of quantum mechanics, the electron is treated as a modified Brownian particle. Here, however, the analysis is based on extensions of the short-time Ornstein-Uhlenbeck description of classical Brownian motion, rather than the approximate, long-time Einstein-Smoluchowski treatment utilized in the earlier work. It is shown that Schrödinger's equation with its proper probabilistic interpretation emerges as an asymptotic description of such a system. After reviewing relevant aspects of Brownian motion, the appropriate equation for the displacement distribution in (...) the Ornstein-Uhlenbeck framework is derived. The Brownian system is then coupled to external potentials via a modified Lagrangian formulation, resulting in coupled equations which, except for transient terms, are shown to be equivalent to Schrödinger's equation. These transients imply that the short-time stochastic model, while reproducing the early successes of quantum mechanics, is, in principal, experimentally distinguishable from it. (shrink)

This article is the attempt at a dialogue with Bruce McCormack about the position he espoused in The Cambridge Companion to Karl Barth concerning the relation between God's Election of grace and God's Triunity. I had criticized McCormack's position in my book, Divine Freedom and the Doctrine of the Immanent Trinity (2002), but I did not elaborate on it in great detail. To develop the dialogue I will: 1) consider McCormack's claim that in CD II/2 Barth made Jesus Christ “rather (...) than” the Eternal Logos the subject of election; 2) consider what Barth means when he speaks of Jesus Christ “in the beginning”; 3) compare McCormack's thesis that the Father never had regard for the Son, apart from the humanity to be assumed, with Barth's belief that we must not dispute the eternal will of God which “precedes even predestination”; 4) analyze in detail McCormack's rejection of Barth's belief that the logos asarkos in distinction from the logos incarnandus is a necessary concept in trinitarian theology; 5) discuss Barth's concept of the divine will in relation to the concept advanced by McCormack and suggest that McCormack has fallen into the error of Hermann Schell by thinking that God in some sense takes his origin from himself, so that God would only be triune if he elected us; 6) explain why it is a problem to hold, as McCormack does, that God's self-determination to be triune and his election of us should be considered one and the same act; and finally 7) explain McCormack's confusion of time and eternity in his latest article on the subject in the February, 2007 issue of the Scottish Journal of Theology, and his own espousal of a kind of indeterminacy on God's part (which he theoretically rejects). (shrink)

In lieu of an abstract, here is a brief excerpt of the content:SOME DOGMATIC CONSEQUENCES OF PAUL F. KNITTER'S UNITARIAN THEOCENTRISM PAUL D. MOLNAR St. John's University Jamaica, New York EACTIONS TO Paul Knitter's No Other Nanie? vary from criticizing his "unitarian theocentrism" 1 and his sliding away from "creedal Chrisitology" 2 to unequivocail endorsement of his" less Christocentric approach to a theo1ogy of religions;" 3 this shows the challenge Knitter poses to current dogmatics. This 1arHcile w1ll (...) explore three critical dogmatic issues related to Knitter's non-normative ChristoJogy. First, can the idea that Jesus is one savior among others be defonded froni within the Christian-Catholic 1tradition without yie1ding the truth of Christology? Second, if "Jesus remains universailly normativ ;e " for Christians while " other revelations or rev;ea:lers might also be universaUy normative," then does this not p:vomote some form of docetic Christology and lead to a unitarianism, exduded by the naiture of the God revealed in Christ? Third, on the basis of " l'eligious experience " Knitter olaims to perceive an" evolution from ecolesiocentrism to chrfatocentrism to theocentrism" and finally to "soteriooentrism." 4 Is there 1!1ea1ly such an evolution? And if there is noit, oan those who de- ~end the tradition succeed by arguing from experience and praxis rather than from revelation and faith? 5 Moreover, if 1"Review Symposium: Paul Knitter's No Other Name?: A Critical Survey of OMistian Attitudes toward the World Religions," in Horizons 13 (1986): 116-135. This is the view of Daniel Sheridan, p. llS. 2 This is the view of Denise Carmody. Ibid., p. 122. s This is the view of William Cenkner. Ibid., p. 127. 4 Ibid., pp. 133-34. 5 Denise Carmody, e.g., believes that we should stress praxis more than 449 450 PAUL D. MOLNAR we think the tradition should not be defended, have we not ceased to think about theological truth? Rather, have we not made divinity itself indis:tingiuishab1e from our human experiences and praxis at the outset? And does this not open the door to both polytheism allJd pantheism? By making God hut noit Christ normative, Knitter's " nonnormati ¥e" Christology re-1transiates the truth of Jesus' oonsubstantiality with the Father into the content of a myth, an experienice or a vailue judgment having no re1ality in itseH.6 It then defines :reveiLation and salvation.aocording to a unitarian view of God. While Knitter denies this,7 his reasoning aictuaUy is unitarian: In my proposed model, Jesus remains universally normative, but I am asking whether Christians can recognize that other revelations or revealers might also be universally normative. Could there be a complementary uniqueness among the religious traditions of the world? To try to answer that question, 'intellectual conversion;... is a requisite. But it will have to be an intellectual conversion that walks more than' the way to Nicea and Chalcedon'... only on the basis of the praxis of authentic dialogue-grounded in intellectual, moral, and religious conversion-can we know the unique~ ness of Christ.8 doctrine without relativizing Christ. Thus, for her, Rahner's Christology does not mean " that Christians cannot be open to the Buddha or Lord Krishna," Ibid., p. 126. The problem is that this very thinking already relativizes Christ. 6 Even theologians who do not intend the radical views of John Hick run a similar risk by beginning Christology from below in the manner of Paul Knitter. Cf., e.g., Edward L. Krasevac, O.P., "' Christology From Above' And 'Christology From Below '," The Thomist, 51 (1987) : 299-306, arguing that "Christological faith is an apostolic faith that has its origins in a historical process which began with the public ministry of our Lord...." (p. 300) causes us to ask what makes Christology true? Is it "the actual apostolic process " (306) or is it Jesus as the Lord who is and remains the sole foundation and validation for faith in any age? Does this approach not leave the door open to the kind of evolution which Knitter claims to have discovered in Christianity, which then enables him to move beyond Jesus as the only Lord and Savior? 1 Review Symposium, Horizons, p. 131. s Ibid., p. 133. KNITTER'S UNITARIAN THEOCENTRISM 451 Here the ha:.sis... (shrink)

Why is it that most among the relatively few moral philosophers since Kant who, like J. S. Mill, have discussed the question whether there can be moral duties to oneself, have answered it negatively? One reason is that those philosophers have supposed that all moral action must be, inter alia, social; and they may have thought so because of their commitment to what is here called a 'corporationist' moral view. But such a conception of morality as social is objectionable because (...) it does not square with ordinary opinion and because it introduces an artificial division between types of action which go together in real life. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:MOLTMANN'S POST-MODERN MESSIANIC CHRISTOLOGY: A REVIEW DISCUSSION 1 PAUL D. MOLNAR St. Johns University Jamaica, New York 0 VER TWENTY-FIVE years ago Jiirgen Moltmann's response to Karl Barth's suggestion that it might be wise to " accept the doctrine of the immanent trinity of God " 2 indicated the future of his theology: " in studying C.D. at these points I always lost my breath. I suspect you (...) are right but I cannot as yet or so quickly enter into this right." Moltmann believed he could present the " economic Trinity " in such a way that " in the foreground, and then again in the background, it would be open to an immanent Trinity... the Holy Spirit is first the Spirit of the raising of the dead and then as such the third person of the Trinity." 3 Moltmann's The Way of Jesus Christ reflects the same onesidedness that Barth had criticized in his theology of hope, and this predicament leads to his own distinct messianic christology, as we shall see. This third volume in Moltmann's systematic theology, following his Trinity and the Kingdom and God in 1 The Way of Jesits Christ: Christology fo Messianic Dimensions. By Jiirgen Moltmann. Translated by Margaret Kohl (San Francisco: Harper San Francisco, a division of HarperCollins Publishers, 1990). Pp. vii + 388. $24.95. This volume has a name index only. The Way of Jesits Christ will henceforth be cited in the text of this article by page numbers within parentheses, without further qualification. 2 Karl Barth Letters 1961-1968, ed. Jurgen Fangmeier and Hinrich Stoevesandt, trans. and ed. by Geoffrey W. Bromiley (Grand Rapids: Eerdmans, 1981)' p. 175. 3 Ibid., p. 348. Barth's Church Dogmatics is usually abbreviated as C.D. 669 670 PAUL D. MOLNAR Creation,4 is intended to lead to a fourth volume on Redemption. Like Moltmann's other works it is tightly written, difficult, intriguing and informative. His writing is clear and his position certainly is developed with a commendable systematic rigor. Throughout this book, which contains seven chapters with clear headings indicating the topics to be treated, the reader is compelled to admire Moltmann's ability to weave together immense amounts of scriptural and systematic data without losing his own position in the process. While the wealth of information alone makes this book worth studying, there is much more than information here. Yet the problem with this book is apparent throughout, i.e., Moltmann attempts to reconceive christology not from a superior knowledge of the person and work of Jesus Christ as presented in scripture but from the community's experience of Jesus Christ in the present. Hence he begins his own " pneumatological christology " with the experience of discipleship (xiv) and argues against the traditional christologies, on the basis of " Christopraxis " which he says is "the source from which christology springs " (41). But can we say that our discipleship is the "source" of christology when, according to Matt. 16 :17, flesh and blood did not disclose who Jesus was-rather, this was revealed by God? This substitution of experience for a real action of the trinity within history is the weakness of Moltmann's bold attempt to revise christology.5 I hope to show how this problem affects Moltmann's method and conclusions. While I agree with Moltmann's intention to present a christology which makes sense in a post-modern environment, I hope to illustrate that by beginning with experience rather than with the Word of God revealed, 4 Jiirgen Moltmann, God in Creation: A New Theology of Creation and the Spirit of God (San Francisco: Harper and Row, 1985), pp. xv-365. Hereafter cited within the text of the article as Creation. J iirgen Moltmann, The Trinity and the Kingdom: The Doctrine of God (San Francisco: Harper and Row, 1981), pp. xvi-256. Hereafter cited within the text of the article as Trinity. 5 As I indicated in Theological Studies vol. 51 (p. 684), this is also a serious predicament in his theology of the trinity and of creation. MOLTMANN'S POST-MODERN CHRISTOLOGY 671 he is unable to escape the " Jesuology " which he criticizes in Rahner and the metaphysical view that... (shrink)

The molecular mechanism of temperature‐dependent sex determination (TSD) is a long‐standing mystery. How is the thermal signal sensed, captured and transduced to regulate key sex genes? Although there is compelling evidence for pathways via which cells capture the temperature signal, there is no known mechanism by which cells transduce those thermal signals to affect gene expression. Here we propose a novel hypothesis we call 3D‐TSD (the three dimensions of thermolabile sex determination). We postulate that the genome has capacity to remodel (...) in response to temperature by changing 3D chromatin conformation, perhaps via temperature‐sensitive transcriptional condensates. This could rewire enhancer–promoter interactions to alter the expression of key sex‐determining genes. This hypothesis can accommodate monogenic or multigenic thermolabile sex‐determining systems, and could be combined with upstream thermal sensing and transduction to the epigenome to commit gonadal fate. (shrink)

The prevailing view among historians of science holds that Charles Darwin became a convinced transmutationist only in the early spring of 1837, after his Beagle collections had been examined by expert British naturalists. With respect to the fossil vertebrate evidence, some historians believe that Darwin was incapable of seeing or understanding the transmutationist implications of his specimens without the help of Richard Owen. There is ample evidence, however, that he clearly recognized the similarities between several of the fossil vertebrates he (...) collected and some of the extant fauna of South America before he returned to Britain. These comparisons, recorded in his correspondence, his diary and his notebooks during the voyage, were instances of a phenomenon that he later called the “law of the succession of types.” Moreover, on the Beagle, he was following a geological research agenda outlined in the second volume of Charles Lyell’s Principles of Geology, which implies that paleontological data alone could provide an insight into the laws which govern the appearance of new species. Since Darwin claims in On the Origin of Species that fossil vertebrate succession was one of the key lines of evidence that led him to question the fixity of species, it seems certain that he was seriously contemplating transmutation during the Beagle voyage. If so, historians of science need to reconsider both the role of Britain’s expert naturalists and the importance of the fossil vertebrate evidence in the development of Darwin’s ideas on transmutation. (shrink)

Abstract.In evolving to its great size the human brain has retained the distinctive features and chemistry of three kinds of brains that reflect an ancestral relationship to reptiles, early mammals, and late mammals. It constitutes, so to speak, a psychencephalon comprised of three‐brains‐in‐one, a triune brain. In the evolution from reptiles to mammals two key changes were the development of nursing and maternal care. Through the agency of “newer” parts of the brain a parental concern for family eventually generalizes not (...) only to other members of the species but to the entire biosphere, a psychological development that amounts to the evolution of responsibility and what we call conscience. Given our freedom to decide “yes” or “no” on various issues, we need not look beyond the evolving family to find a reason for being, an ethic to live by. (shrink)

In this work Paul Murray explores which style of rationality is most appropriate to Christian theology in the contemporary pluralist, postfoundationalist, ...

In summary, then, I have presented a program for analysis of physical causal statements in terms of the following metaphysical primitives: space (made up of ordered points), time (also ordered and punctiliar), causal density, haecceity and causal necessity. These can be ‘read off’ the theories in question. I claim that theevent-singular cases are crucial, and that other cases can be reduced to this via set theory and (causal) modal logic. I have given several examples of this sort of translation and (...) a rough indication of how more complicated cases could be dealt with. (shrink)

In this study, we examined the effects of emotional experience, a relatively new dimension of emotional knowledge that gauges the ease with which words evoke emotional experience, on abstract word processing in the Stroop task. In order to test the context-dependency of these effects, we accentuated the saliency of this dimension in Experiment 1A by blocking the stimuli such that one block consisted of the stimuli with the highest emotional experience ratings and the other block consisted of the stimuli with (...) the lowest emotional experience ratings. We attenuated the saliency of this dimension in Experiment 1B by intermixing the stimuli. We observed slower color naming performance for words with higher emotional experience ratings only in Experiment 1A, suggesting that the dimension of emotional experience is an aspect of semantic representation for abstract words but that its influence can be modulated by context. We interpret these results more generally using Vigliocco, Meteyard, Andrews, and Kousta's framework of semantic representation, and more specifically using Cohen, Dunbar, and McClelland's model of Stroop task performance. (shrink)